Native Proteins and Derivatives
Biotium Primary Antibody CD227 EMA Episialin Mucin 1 E29 CF740 1/EA
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack In immunohistochemical assays it superbly stains routine formalin/paraffin carcinomas Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
Cayman Chemical 8AzIdoadenosIn5OtrIphos 2.7mg
A clickable form of ATP; has been used in the synthesis of fluorescent probes for live cell imaging; radiolabeled forms have been used as photoaffinity labels for various proteins, including viral RNA polymerase and Kir6.2
Cayman Chemical 2 3-O- 5-ChloronthrnIloy 3.3mg
Fluorescent ATP derivatives; an inhibitor of mammalian AC1, AC2, and AC5 (Kis = 80, 490, and 45 nM, respectively), B. anthracis edema factor AC toxin (Ki = 170 nM), and B. pertussis CyaA (Ki = 350 nM)
Cayman Chemical 6ThIogunosIn5OtrIphosp 2.7mg
An active metabolite of 6-thioguanine and azathioprine; binds to a variety of GTPases but selectively inhibits activation of Rac1 and Rac2 over Cdc42 in primary human CD4+ T cells stimulated with anti-CD3 and anti-CD28 antibodies; inhibits T cell receptor-stimulated proliferation of T cells and reduces CD28-dependent T cell survival in vitro in isolated mouse splenocytes; increases survival in a mouse model of heart transplantation at 0.5 mg/kg
Bioss KD-Validated Fibronectin 1 Rab
Fibronectin 1 Primary Antibody Unconjugated Public Immunogen Range 1-2477/2477 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ABclonal Technology APOE Rabbit pAb
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Abcam Calmidazolium chloride, Calmodulin inhibitor, 10MG
MW 687.7 Da, Purity >98%. Calmodulin inhibitor (IC₅₀ = 10 nM). Elevates intracellular calcium, independent of calmodulin inhibition. Additionally inhibits adenylyl cylase activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Native Herpes simplex virus HSV2 protein, 1ML
Native Herpes simplex virus HSV2 protein is a Full Length protein and expressed in Native.
Protein/ Peptide/ Enzyme Synonyms: Herpes Simplex Virus Type 2
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tanespimycin (17-AAG), HSP90 inhibitor, 5MG
MW 585.7 Da, Purity >98%. Potent, selective HSP90 inhibitor (IC₅₀ = 5 nM). Anticancer activity, including cytostatic, proapoptotic and antiangiogenic properties in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Trifluoperazine dihydrochloride, calmodulin antagonist, 1G
MW 480.42 g/mol, Purity >99%. Cell-permeable calmodulin antagonist. Dopamine receptor antagonist. Stimulates ER Ca²+ ATPase activity at low concentrations and inhibits at higher concentrations. Antipsychotic.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sitagliptin Phosphate Monohydrate, 1G
MW 523.32 Da, Purity >=98%. Anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Geldanamycin, Hsp90 inhibitor, 5MG
MW 560.64 g/mol, Purity >98%. Selective Hsp90 inhibitor. Binds the ATP site of Hsp90 and inhibits chaperone activity. A benzoquinone ansamycin antibiotic. Also inhibits the Hsp90 paralog GRP94. Exhibits various cellular actions including gene expression, cell proliferation, apoptosis and angiogenesis.
The product is subject to the following: Abcam Restricted Use Statement